Nucleosides and Analogues
Selleck Chemical LLC FAD disodium salt-E0705-5MG
Flavin Adenine Dinucleotide Disodium is a redox cofactor more specifically a prosthetic group of a protein involved in several important enzymatic reactions in metabolism
Selleck Chemical LLC BRM/BRG1 ATP Inhibitor-1
BRM/BRG1 ATP Inhibitor-1 (Compound 14) is an orally active inhibitors of Brahma Homolog (BRM)/SMARCA2 (BRG1) with IC50s below 0 005 M
Cayman Chemical 3-AcetylpyrIdIn NAD 100mg
A more lipid soluble form of 11(Z)14(Z)-eicosadienoic acid
Cayman Chemical N6-benzoyl-2-DeoxyadenosIn 1g
An agonist of mGluRs (EC50s 15 2 40 23 and 82 UM for mGluR1 -2 -3 -5 and -6 respectively in CHO cells expressing recombinant receptors and 800 UM for mGluR4 in baby hamster kidney cells) increases cAMP accumulation in adult rat cerebral cortex slices (EC50 47 8 UM) but not in isolated rat embryonic neurons or neonatal glial cells at 1-1000 UM increases phosphoinositide hydrolysis in neonatal rat cerebral cortex and hippocampal slices at 10-1000 UM induces convulsions in neonatal rats (ED50 100 mg/kg) an effect that can be reversed by administration of the NMDA receptor antagonists LY233053 and LY274614
Cayman Chemical N6-benzoyl-2-DeoxyadenosIn 10g
A small molecule that induces proliferation of primary human hepatocytes in vitro
TARGETMOL CHEMICALS INC 6-THIO-2-DEOXYGUANOSINE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 6-Thio-2'-Deoxyguanosine ((beta)-TGdR) is a nucleoside analog and telomerase substrate. purity: 99%
Cayman Chemical 5-chloro-5-DeoxyadenosIn 1g
An internal standard for the quantification of acetaminophen by GC- or LC-MS
Cayman Chemical N6-Methyl-2-deoxyadenosIn 50mg
An internal standard for the quantification of indole-3-acetic acid by GC- or LC-MS
Cayman Chemical 2-Fluoro-2-deoxyadenosIn 500mg
An ionizable cationic lipid (pKa 7.12) intravenous administration of LNPs containing (S)-C12-200 and encapsulating mRNA encoding Cre recombinase increase the percentage of tdTomato hepatocytes endothelial cells and Kupffer cells in the livers of Ai14 mice greater than (R)-C12-200-containing and Cre mRNA-encapsulating LNPs
Cayman Chemical N6-Methyl-2-deoxyadenosIn 10mg
A polyphenol flavonoid dimer with diverse biological activities binds to PlGF and VEGF (Kds 394 and 476 nM respectively) increases the activity of JAK2 (EC50 660 nM) scavenges superoxide radicals (IC50 14.7 UM) inhibits the cytopathic effects of HIV-1 in MT-4 cells (IC50 14 Ug/ml) increases the proliferation of isolated mouse splenocytes and peritoneal macrophages from 25-100 UM and DAMI megakaryoblasts (EC50 8.58 UM) prevents decreases in the number of platelets in peripheral blood and megakaryocytes in the bone marrow in a mouse model of carboplatin-induced thrombocytopenia at 50 mg/kg
Cayman Chemical 5-Formyl-2-deoxyurIdIn 250mg
13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian LOs. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 UM{592880} and down regulates the expression of the IRGpIIb/IIIa receptor.{591}
Cayman Chemical 5-Bromo-2-deoxyurIdIn 50mg
A potent competitive inhibitor of PKC PKG and PKA with Ki values of 18 0.87 and 1.9 UM repectively
Cayman Chemical 5-Bromo-2-deoxyurIdIn 250mg
A propanolamine that potently selectively and non-competitively antagonizes the NR2B subunit of NMDA receptors (IC50 50 nM) does not inhibit other NMDA subunits AMPA receptors or kainate receptors has neuroprotective effects in vitro and in vivo
Cayman Chemical 5-Chloro-2-deoxyurIdIn 100mg
A cannabimimetic indole that binds the CB1 and CB2 receptors with EC50 values of 21 and 140 nM respectively intended for research and forensic applications
Cayman Chemical 5-Chloro-2-deoxyurIdIn 50mg
An antibiotic that inhibits DOXP reductoisomerase a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis against both Gram-negative and Gram-positive bacteria and the human malarial parasite P. falciparum (IC50 290-370 nM)